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L-Serine
Detailed Product Description
L-Serine is one of the two biological amino acids with a hydroxyl substituted side chain, and thus is hydrophilic in character. The L-serine side chain is a hydroxymethyl (HOCH2-) group. Serine is biosynthesized from the glycolysis intermediate 3-phosphoglycerate through the formation of 3-phosphohydroxypyruvate and 3-phosphoserine as intermediates. In turn, serine can be converted into the gluconeogenesis intermediate 3 -phosphglycerate.
Serine is also a precursor for the biosynthesis of glycine, cysteine, and selenocysteine.
The role of L-serine in brain development and function has been reviewed.
The biosynthesis and degradation of L-serine in Escherichia coli has been discussed.
A comprehensive review of the chemistry of serine has been published.
The influence of pulsed applications of serine on polyglucose synthesis by Fusobacterium nucleatum cultures has been studied.
Supplementation of minimal media with serine has been shown to restore growth in Escherichia coli that lack the PII and GlnK genes.
Precautions and Disclaimer
For Laboratory Use Only. Not for drug, household or other uses.
Preparation Instructions
This product is soluble in water (50 mg/ml), yielding a clear, colorless solution. The solubility of L -serine in water has also been reported to be 250 mg/ml (20 °C).
