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Acetyl Coenzyme A sodium salt
Detailed Product Description
Product Description
Appearance: White powder
Molecular Formula: C23H38N7O17P3S (for free acid)
Molecular Weight: 809.6 (for free acid)
EM(260nm) = 16,400 (water)
EM(259nm) = 15,400 (0.1 M PO4 Buffer, pH 7)
EM(232nm) = 8,700 (water)
A8071 is prepared enzymatically by reacting Coenzyme A with Acetyl Phosphate and Phosphotransacetylase.
The product is purified by ion exchange chromatography. Several methods of preparation and
methods for the determination of Acetyl CoA and other CoA derivatives have been described in the literature.
Coenzymes comprise a class of molecules, generally derived from vitamins, which function catalytically in enzyme systems.
The acetic acid moiety which is bound by a high-energy bond (free energy 34.3 kJ/mol) to the -SH group of Coenzyme A is a precursor to fatty acids, steroids and other naturally occurring compounds, such as terpenes and acetogenins present in plants.
The biosynthetic pathways for Acetyl CoA have been illustrated.
In the transfer reaction by Acetyl CoA of the C2 acetyl fragment, either the carboxyl group or the methyl group may react (electrophilic vs. nucleophilic reaction, respectively).
